human IL24 Adenovirus

Name 
Ad-h-IL24
Cat No 
ADV-230082
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IL24.

ADV-230082
Ad-h-IL24

Ready-to-use Adenovirus expressing Human IL24 (interleukin 24). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C49A; FISP; IL10B; MDA7; MOB5; ST16
Description (Vector)
IL24 encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene ID
11009
Gene Name (Vector)
interleukin 24
Gene Symbol
IL24
HGNC ID
HGNC:11346
ORF Size (aa)
624
RefSeq ID
NM_006850
RefSeq Synonyms
NM_006850, NM_001185158, NM_001185157, NM_001185156, BC009681,
Species
human
UniGene ID
Hs.719320

Related Citations

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.