human ZFP91 Adenovirus

Name 
Ad-h-ZFP91
Cat No 
ADV-228225
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human ZFP91.

ADV-228225
Ad-h-ZFP91

Ready-to-use Adenovirus expressing Human ZFP91 (ZFP91 zinc finger protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DMS-8; drug resistance-associated sequence in melanoma 8; DSM-8; E3 ubiquitin-protein ligase ZFP91; FKSG11; penta zinc finger protein; PZF; RING-type E3 ubiquitin transferase ZFP91; ZFP-91; zinc finger protein 757; zinc finger protein 91 homolog; zinc finger protein homologous to Zfp91 in mouse; ZNF757
Description (eCommerce)
ZFP91 (zinc finger protein 91 homolog) is an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilization and activation of MAP3K14/NIK. ZFP91 thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. ZFP91 may also play an important role in cell proliferation and/or anti-apoptosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96JP5].
Description (Vector)
ZFP91 is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. This protein functions as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. Alternative splicing results in multiple transcript variants. A read-through transcript variant composed of ZFP91 and the downstream CNTF gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. A ZFP91-related pseudogene has also been identified on chromosome 2.
Gene ID
80829
Gene Name (eCommerce)
ZFP91 zinc finger protein
Gene Name (Vector)
ZFP91 zinc finger protein
Gene Symbol
ZFP91
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1710
ORF Size (bp)
1710 bp
Protein Name (eCommerce)
E3 ubiquitin-protein ligase ZFP91
RefSeq ID
NM_053023
RefSeq Synonyms
NM_053023, NM_001197051, BC051743,
Research Areas
Ubiquitination,Zinc-finger
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
ZFP91 (zinc finger protein 91 homolog) is an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilization and activation of MAP3K14/NIK. ZFP91 thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. ZFP91 may also play an important role in cell proliferation and/or anti-apoptosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q96JP5].
UniGene ID
Hs.524920
UniProt ID (eCommerce)
Q96JP5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.