human YARS Adenovirus

Name 
Ad-h-YARS
Cat No 
ADV-227946
Availability
4-5 weeks

This is an Adenovirus expressing Human MBOAT7.

ADV-227946
Ad-h-YARS

Ready-to-use Adenovirus expressing Human YARS (tyrosyl-tRNA synthetase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CMTDIC; tyrosine tRNA ligase 1, cytoplasmic; tyrosine--tRNA ligase, cytoplasmic; tyrosyl--tRNA ligase; Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase, cytoplasmic; TYRRS; YRS; YTS
Description (eCommerce)
The YARS gene encodes the protein Tyrosine--tRNA ligase, cytoplasmic, also known as Tyrosyl-tRNA synthetase. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution [taken from NCBI Entrez Gene (Gene ID: 8565)].
Description (Vector)
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
Gene ID
8565
Gene Name (eCommerce)
tyrosyl-tRNA synthetase
Gene Name (Vector)
tyrosyl-tRNA synthetase
Gene Symbol
YARS
HGNC ID
HGNC:12840
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1587
ORF Size (bp)
1587 bp
Protein Name (eCommerce)
Tyrosine--tRNA ligase, cytoplasmic
RefSeq ID
NM_003680
RefSeq Synonyms
NM_003680, BC016689, BC004151, BC001933,
Research Areas
Apoptosis,Gene Expression,Interleukin Signaling,Neurobiology,Neurodegeneration,Neurodevelopment,RNA Binding,Signal Transduction,Translational Control,tRNA Binding
Research Areas (Faceted)
signal_transduction,cell_biology,genetics,transcription_translation,signal_transduction,immunology,neurobiology,developmental_biology,genetics,transcription_translation
Species
human
Target Sentence
The YARS gene encodes the protein Tyrosine--tRNA ligase, cytoplasmic, also known as Tyrosyl-tRNA synthetase. Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution [taken from NCBI Entrez Gene (Gene ID: 8565)].
UniGene ID
Hs.706890
UniProt ID (eCommerce)
P54577

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.