human XIAP Adenovirus
This is an Adenovirus expressing Human XIAP.
ADV-227883
Ad-h-XIAP
Ready-to-use Adenovirus expressing Human XIAP (X-linked inhibitor of apoptosis). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
API3; BIRC4; hIAP-3; hIAP3; IAP-3; ILP1; MIHA; XLP2
Description (Vector)
XIAP encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Gene ID
331
Gene Name (Vector)
X-linked inhibitor of apoptosis
Gene Symbol
XIAP
HGNC ID
HGNC:592
ORF Size (aa)
1494
ORF Size (bp)
1494 bp
RefSeq ID
NM_001167
RefSeq Synonyms
NM_001204401, NM_001167, BC032729,
Species
human
UniGene ID
Hs.356076
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.