human USP4 Adenovirus

Name 
Ad-h-USP4
Cat No 
ADV-227320
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human USP4.

ADV-227320
Ad-h-USP4

Ready-to-use Adenovirus expressing Human USP4 (ubiquitin specific peptidase 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
deubiquitinating enzyme 4; ubiquitin carboxyl-terminal esterase 4; ubiquitin carboxyl-terminal hydrolase 4; ubiquitin specific peptidase 4 (proto-oncogene); ubiquitin specific protease 4 (proto-oncogene); ubiquitin thioesterase 4; ubiquitin thiolesterase 4; ubiquitin-specific processing protease 4; Ubiquitin-specific-processing protease 4; ubiquitous nuclear protein homolog; UNP; Unph
Description (eCommerce)
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 4 (USP4) is a member of this family.
Description (Vector)
USP4 is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
7375
Gene Name (eCommerce)
ubiquitin specific peptidase 4
Gene Name (Vector)
ubiquitin specific peptidase 4
Gene Symbol
USP4
HGNC ID
HGNC:12627
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2892
ORF Size (bp)
2892 bp
Protein Name (eCommerce)
Ubiquitin carboxyl-terminal hydrolase 4
RefSeq ID
NM_003363
RefSeq Synonyms
NM_199443, NM_003363, NM_001251877, BC125131, BC125130,
Research Areas
Cancer,Lysosome,Ubiquitination
Research Areas (Faceted)
cancer,cell_biology
Species
human
Target Sentence
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 4 (USP4) is a member of this family.
UniGene ID
Hs.714416
UniProt ID (eCommerce)
Q13107

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.