human USP28 Adenovirus

Name 
Ad-h-USP28
Cat No 
ADV-227300
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human USP28.

ADV-227300
Ad-h-USP28

Ready-to-use Adenovirus expressing Human USP28 (ubiquitin specific peptidase 28). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
deubiquitinating enzyme 28; ubiquitin carboxyl-terminal hydrolase 28; ubiquitin carboxyl-terminal hydrolase 28 variant 1; ubiquitin thioesterase 28; ubiquitin thiolesterase 28; ubiquitin-specific-processing protease 28
Description (eCommerce)
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 28 (USP28) is a member of this family.
Description (Vector)
The ubiquitin-dependent protein degradation pathway is essential for proteolysis of intracellular proteins and peptides. Enzymes that remove ubiquitin from ubiquitin-conjugated peptides, like USP28, affect the fate and degradation of intracellular proteins and are essential for maintenance of cell-free ubiquitin pools (Valero et al., 2001).(supplied by OMIM, Mar 2008)
Gene ID
57646
Gene Name (eCommerce)
ubiquitin specific peptidase 28
Gene Name (Vector)
ubiquitin specific peptidase 28
Gene Symbol
USP28
HGNC ID
HGNC:12625
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1752
ORF Size (bp)
1752 bp
Protein Name (eCommerce)
Ubiquitin carboxyl-terminal hydrolase 28
RefSeq ID
NM_020886
RefSeq Synonyms
NM_020886, NM_001346273, NM_001346272, NM_001346271, NM_001346270, NM_001346269, NM_001346268, NM_001346267, NM_001346265, NM_001346264, NM_001346263, NM_001346262, NM_001346261, NM_001346260, NM_001346259, NM_001346258, NM_001346257, NM_001346255, NM_001346254, NM_001346253, NM_001346252, NM_001301029, BC065928,
Research Areas
Apoptosis,DNA Damage/Repair,Ubiquitination
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 28 (USP28) is a member of this family.
UniGene ID
Hs.503891
UniProt ID (eCommerce)
Q96RU2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.