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human TNFSF15 Adenovirus

Name 
Ad-h-TNFSF15
Cat No 
ADV-226104
Availability
4-5 weeks

This is an Adenovirus expressing Human TNFSF15.

ADV-226104
Ad-h-TNFSF15

Ready-to-use Adenovirus expressing Human TNFSF15 (tumor necrosis factor superfamily member 15). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
TL1; TL1A; TNLG1B; VEGI; VEGI192A
Description (Vector)
TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
9966
Gene Name (Vector)
tumor necrosis factor superfamily member 15
Gene Symbol
TNFSF15
HGNC ID
HGNC:11931
ORF Size (aa)
756
RefSeq ID
NM_005118
RefSeq Synonyms
NM_005118, NM_001204344, BC104463, BC104462, BC074941, BC074940, BC069435,
Species
human
UniGene ID
Hs.241382

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.