human SRP72 Adenovirus

Name 
Ad-h-SRP72
Cat No 
ADV-224343
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SRP72.

ADV-224343
Ad-h-SRP72

Ready-to-use Adenovirus expressing Human SRP72 (signal recognition particle 72). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BMFF; BMFS1; epididymis luminal protein 103; HEL103; signal recognition particle 72 kDa protein; signal recognition particle 72kD; signal recognition particle 72kDa; signal recognition particle subunit SRP72; SRP72
Description (eCommerce)
Signal recognition particle subunit SRP72 is the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure [taken from NCBI Entrez Gene (Gene ID: 6731)].
Description (Vector)
SRP72 encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
6731
Gene Name (eCommerce)
signal recognition particle 72
Gene Name (Vector)
signal recognition particle 72
Gene Symbol
SRP72
HGNC ID
HGNC:11303
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2016
ORF Size (bp)
2016 bp
Protein Name (eCommerce)
Signal recognition particle subunit SRP72
RefSeq ID
NM_006947
RefSeq Synonyms
NM_006947, NM_001267722, BC160164,
Research Areas
Gene Expression,Metabolism/Metabolic Process,RNA Binding,Translational Control,Transport
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Signal recognition particle subunit SRP72 is the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure [taken from NCBI Entrez Gene (Gene ID: 6731)].
UniGene ID
Hs.237825
UniProt ID (eCommerce)
O76094

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.