human SPO11 Adenovirus
This is an Adenovirus expressing Human SPO11.
ADV-224218
Ad-h-SPO11
Ready-to-use Adenovirus expressing Human SPO11 (SPO11, initiator of meiotic double stranded breaks). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CT35; SPATA43; TOPVIA
Description (Vector)
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
Gene ID
23626
Gene Name (Vector)
SPO11, initiator of meiotic double stranded breaks
Gene Symbol
SPO11
HGNC ID
HGNC:11250
ORF Size (aa)
1077
ORF Size (bp)
1077 bp
RefSeq ID
NM_012444
RefSeq Synonyms
NM_198265, NM_012444, BC033591,
Species
human
UniGene ID
Hs.159737
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.