human SPC24 Adenovirus
This is an Adenovirus expressing Human SPC24.
ADV-224132
Ad-h-SPC24
Ready-to-use Adenovirus expressing Human SPC24 (SPC24, NDC80 kinetochore complex component). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hSpc24; kinetochore protein Spc24; SPBC24; SPC24, NDC80 kinetochore complex component, homolog; spindle pole body component 24 homolog
Description (eCommerce)
Kinetechore protein SPC24 acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. SPC24 is required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NBT2].
Gene ID
147841
Gene Name (eCommerce)
SPC24, NDC80 kinetochore complex component
Gene Name (Vector)
SPC24, NDC80 kinetochore complex component
Gene Symbol
SPC24
HGNC ID
HGNC:26913
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
594
ORF Size (bp)
594 bp
Protein Name (eCommerce)
Kinetochore protein Spc24
RefSeq ID
NM_182513
RefSeq Synonyms
NM_182513, NM_001317033, NM_001317032, NM_001317031, BC105039, BC105037,
Research Areas
Cell Cycle,Cell Division,PLK1 Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,signal_transduction
Species
human
Target Sentence
Kinetechore protein SPC24 acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. SPC24 is required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NBT2].
UniGene ID
Hs.381225
UniProt ID (eCommerce)
Q8NBT2
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.