human SLC7A11 Adenovirus

Name
Ad-h-SLC7A11

Cat No
ADV-223586

Availability
4-5 weeks

This is an Adenovirus expressing Human SLC7A11.

ADV-223586

Ad-h-SLC7A11

Ready-to-use Adenovirus expressing Human SLC7A11 (solute carrier family 7 member 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CCBR1; xCT

Description (Vector)

SLC7A11 encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Gene ID

23657

Gene Name (Vector)

solute carrier family 7 member 11

Gene Symbol

SLC7A11

HGNC ID

HGNC:11059

ORF Size (aa)

1506

ORF Size (bp)

1506 bp

RefSeq ID

NM_014331

RefSeq Synonyms

NM_014331, BC012087,

Species

human

UniGene ID

Hs.390594

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.