human SLC12A6 Adenovirus

Name 
Ad-h-SLC12A6
Cat No 
ADV-223092
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human SLC12A6.

ADV-223092
Ad-h-SLC12A6

Ready-to-use Adenovirus expressing Human SLC12A6 (solute carrier family 12 member 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ACCPN; electroneutral potassium-chloride cotransporter 3; KCC3; KCC3A; KCC3B; K-Cl cotransporter 3; potassium chloride cotransporter 3; potassium chloride cotransporter KCC3a-S3; potassium-chloride transporter-3a; potassium-chloride transporter-3b; solute carrier family 12 (potassium/chloride transporter), member 6; solute carrier family 12 (potassium/chloride transporters), member 6; solute carrier family 12 member 6
Description (eCommerce)
K-Cl cotransporter 3 (KCC3) mediates electroneutral potassium-chloride cotransport. KCC3 may be activated by cell swelling. It may also contribute to cell volume homeostasis in single cells [taken from NCBI Entrez Gene (Gene ID: 9990)].
Description (Vector)
SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.
Gene ID
9990
Gene Name (eCommerce)
solute carrier family 12 member 6
Gene Name (Vector)
solute carrier family 12 member 6
Gene Symbol
SLC12A6
HGNC ID
HGNC:10914
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2832
ORF Size (bp)
2832 bp
Protein Name (eCommerce)
Solute carrier family 12 member 6
RefSeq ID
NM_005135
RefSeq Synonyms
NM_133647, NM_005135, NM_001042497, NM_001042496, NM_001042495, NM_001042494, BC126243, BC126241, BC070107, BC051744,
Research Areas
Angiogenesis,Transport
Research Areas (Faceted)
cancer,cell_biology,developmental_biology
Species
human
Target Sentence
K-Cl cotransporter 3 (KCC3) mediates electroneutral potassium-chloride cotransport. KCC3 may be activated by cell swelling. It may also contribute to cell volume homeostasis in single cells [taken from NCBI Entrez Gene (Gene ID: 9990)].
UniGene ID
Hs.510939
UniProt ID (eCommerce)
Q9UHW9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.