human SCN5A Adenovirus

Name
Ad-h-SCN5A

Cat No
ADV-222374

Availability
4-5 weeks

This is an Adenovirus expressing Human SCN5A.

ADV-222374

Ad-h-SCN5A

Ready-to-use Adenovirus expressing Human SCN5A (sodium voltage-gated channel alpha subunit 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CDCD2; CMD1E; CMPD2; HB1; HB2; HBBD; HH1; ICCD; IVF; LQT3; Nav1.5; PFHB1; SSS1; VF1

Description (Vector)

SCN5A is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms.

Gene ID

6331

Gene Name (Vector)

sodium voltage-gated channel alpha subunit 5

Gene Symbol

SCN5A

HGNC ID

HGNC:10593

ORF Size (aa)

5952

ORF Size (bp)

5952 bp

RefSeq ID

NM_000335

RefSeq Synonyms

NM_198056, NM_001160161, NM_001160160, NM_001099405, NM_001099404, NM_000335, BC144621, BC140813,

Species

human

UniGene ID

Hs.517898

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.