human RNF34 Adenovirus

Name
Ad-h-RNF34

Cat No
ADV-221427

Availability
4-5 weeks

This is an Adenovirus expressing Human RNF34.

ADV-221427

Ad-h-RNF34

Ready-to-use Adenovirus expressing Human RNF34 (ring finger protein 34). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CARP-1; CARP1; hRFI; RFI; RIF; RIFF

Description (Vector)

RNF34 contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

Gene ID

80196

Gene Name (Vector)

ring finger protein 34

Gene Symbol

RNF34

HGNC ID

HGNC:17297

ORF Size (aa)

1119

ORF Size (bp)

1119 bp

RefSeq ID

NM_025126

RefSeq Synonyms

NM_194271, NM_025126, NM_001256858, BC007826,

Species

human

UniGene ID

Hs.292804

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.