human RASSF8 Adenovirus

Name 
Ad-h-RASSF8
Cat No 
ADV-220812
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human RASSF8.

ADV-220812
Ad-h-RASSF8

Ready-to-use Adenovirus expressing Human RASSF8 (Ras association domain family member 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C12orf2; HOJ1
Description (Vector)
RASSF8 encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. RASSF8 is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
11228
Gene Name (Vector)
Ras association domain family member 8
Gene Symbol
RASSF8
HGNC ID
HGNC:13232
ORF Size (aa)
1179
ORF Size (bp)
1179 bp
RefSeq ID
NM_007211
RefSeq Synonyms
NM_007211, NM_001164748, NM_001164747, NM_001164746, BC030021,
Species
human
UniGene ID
Hs.696433

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.