human PTPN23 Adenovirus

Name 
Ad-h-PTPN23
Cat No 
ADV-220321
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human PTPN23.

ADV-220321
Ad-h-PTPN23

Ready-to-use Adenovirus expressing Human PTPN23 (protein tyrosine phosphatase, non-receptor type 23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HDPTP; HD-PTP; his domain-containing protein tyrosine phosphatase; protein tyrosine phosphatase TD14; PTP-TD14; tyrosine-protein phosphatase non-receptor type 23
Description (eCommerce)
His domain-containing protein tyrosine phosphatase (HD-PTP) plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. HD-PTP may act as a negative regulator of Ras-mediated mitogenic activity.This protein plays a role in ciliogenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3S7].
Gene ID
25930
Gene Name (eCommerce)
protein tyrosine phosphatase, non-receptor type 23
Gene Name (Vector)
protein tyrosine phosphatase, non-receptor type 23
Gene Symbol
PTPN23
HGNC ID
HGNC:14406
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4911
ORF Size (bp)
4911 bp
Protein Name (eCommerce)
Tyrosine-protein phosphatase non-receptor type 23
RefSeq ID
NM_015466
RefSeq Synonyms
NM_015466, NM_001304482, BC089042,
Research Areas
Cytoskeleton,EGFR Signaling,Kinase/Phosphatase,Phosphatase,Signal Transduction,Transport
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
His domain-containing protein tyrosine phosphatase (HD-PTP) plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. HD-PTP may act as a negative regulator of Ras-mediated mitogenic activity.This protein plays a role in ciliogenesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3S7].
UniGene ID
Hs.25524
UniProt ID (eCommerce)
Q9H3S7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.