human PTF1A Adenovirus

Name 
Ad-h-PTF1A
Cat No 
ADV-220231
Availability
4-5 weeks

This is an Adenovirus expressing Human GZMM.

ADV-220231
Ad-h-PTF1A

Ready-to-use Adenovirus expressing Human PTF1A (pancreas specific transcription factor, 1a). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bHLHa29; PACA; PAGEN2; PTF1-p48
Description (Vector)
PTF1A encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers.
Gene ID
256297
Gene Name (Vector)
pancreas specific transcription factor, 1a
Gene Symbol
PTF1A
HGNC ID
HGNC:23734
ORF Size (aa)
987
ORF Size (bp)
987 bp
RefSeq ID
NM_178161
RefSeq Synonyms
NM_178161, BC172557, BC172252,
Species
human
UniGene ID
Hs.351503

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.