human PSMA3 Adenovirus

Name 
Ad-h-PSMA3
Cat No 
ADV-220094
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GTPBP10.

ADV-220094
Ad-h-PSMA3

Ready-to-use Adenovirus expressing Human PSMA3 (proteasome subunit alpha 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HC8; macropain subunit C8; multicatalytic endopeptidase complex subunit C8; proteasome (prosome, macropain) subunit, alpha type, 3; proteasome component C8; proteasome subunit alpha type-3; proteasome subunit C8; PSC3; testicular secretory protein Li 43
Description (eCommerce)
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSAM3 is member of the peptidase T1A family and is an alpha subunit of the 20S core [taken from NCBI Entrez Gene (GeneID: 5684)].
Description (Vector)
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Gene ID
5684
Gene Name (eCommerce)
proteasome subunit alpha 3
Gene Name (Vector)
proteasome subunit alpha 3
Gene Symbol
PSMA3
HGNC ID
HGNC:9532
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
747
Protein Name (eCommerce)
Proteasome subunit alpha type-3
RefSeq ID
NM_002788
RefSeq Synonyms
NM_152132, NM_002788, BC038990, BC029402, BC005265,
Research Areas
Antigen Processing and Presentation,Apoptosis,B-cell Receptor Signaling,Cell Cycle,Complexome,DNA Damage/Repair,Gene Expression,Hedgehog Signaling,Host-Virus Interactions,Immunology,Interleukin Signaling,JAK-STAT Signaling,NF-kB Signaling,Notch Signaling,Proteasome,RNA Processing,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling,TNF Signaling,Toll-like Receptor Signaling,Ubiquitination,Wnt Signaling
Research Areas (Faceted)
signal_transduction,immunology,cell_biology,signal_transduction,immunology,cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction,developmental_biology,infectious_disease,immunology,signal_transduction,developmental_biology,cell_biology,genetics,transcription_translation,signal_transduction,immunology,genetics,developmental_biology
Species
human
Target Sentence
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSAM3 is member of the peptidase T1A family and is an alpha subunit of the 20S core [taken from NCBI Entrez Gene (GeneID: 5684)].
UniGene ID
Hs.558799
UniProt ID (eCommerce)
P25788

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.