human PPOX Adenovirus
This is an Adenovirus expressing Human PPOX.
ADV-219595
Ad-h-PPOX
Ready-to-use Adenovirus expressing Human PPOX (protoporphyrinogen oxidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PPO; V290M; VP
Description (Vector)
PPOX encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
Gene ID
5498
Gene Name (Vector)
protoporphyrinogen oxidase
Gene Symbol
PPOX
HGNC ID
HGNC:9280
ORF Size (aa)
1434
ORF Size (bp)
1434 bp
RefSeq ID
NM_000309
RefSeq Synonyms
NM_001122764, NM_000309, BC002357,
Species
human
UniGene ID
Hs.517373
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.