human GPX4 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-210463
Availability:
3-5 weeks
Name:
Ad-h-GPX4-shRNA
This is an Adenovirus expressing shRNA for silencing of Human GPX4.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- GPX4
- Gene Name
- glutathione peroxidase 4
- Gene ID
- 2879
- Gene Synonyms
- GPx-4; GSHPx-4; MCSP; PHGPx; SMDS; snGPx; snPHGPx
- ORF Size
- 594 bp
- RefSeq#
- NM_002085
- Gene Description
- Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
- UniGene ID
- Hs.433951
- HGNC ID
- HGNC:4556
Related Products
Product | Cat No. |
---|---|
AAV-h-GPX4 | AAV-210463 |
AAV-m-GPX4 | AAV-260717 |
Ad-h-GPX4 | ADV-210463 |
Ad-m-GPX4 | ADV-260717 |
AAV-h-GPX4-shRNA | shAAV-210463 |
AAV-m-GPX4-shRNA | shAAV-260717 |
Ad-m-GPX4-shRNA | shADV-260717 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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