human POLR2E Adenovirus

Name 
Ad-h-POLR2E
Cat No 
ADV-219394
Availability
4-5 weeks

This is an Adenovirus expressing Human POLR2E.

ADV-219394
Ad-h-POLR2E

Ready-to-use Adenovirus expressing Human POLR2E (RNA polymerase II subunit E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hRPB25; hsRPB5; RPABC1; RPB5; XAP4
Description (Vector)
POLR2E encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11.
Gene ID
5434
Gene Name (Vector)
RNA polymerase II subunit E
Gene Symbol
POLR2E
HGNC ID
HGNC:9192
ORF Size (aa)
633
RefSeq ID
NM_002695
RefSeq Synonyms
NM_002695, NM_001316324, NM_001316323, BC034144, BC004441,
Species
human
UniGene ID
Hs.24301

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.