human POLI Adenovirus

Name 
Ad-h-POLI
Cat No 
ADV-219368
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human POLI.

ADV-219368
Ad-h-POLI

Ready-to-use Adenovirus expressing Human POLI (DNA polymerase iota). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DNA polymerase iota; eta2; polymerase (DNA directed) iota; polymerase (DNA) iota; polymerase (DNA-directed), iota; RAD30 homolog B; RAD30B; RAD3OB
Description (eCommerce)
Pol Iota is a DNA polymerase involved in DNA repair and translesion DNA synthesis. Pol Iota is a member of the Rad30 family of DNA polymerases which exhibit low fidelity when replicating undamaged DNA, and in this context may play a role in the hypermutation of immunoglobulin genes. Pol Iota is also known as RAD30B and is a paralog of RAD30A, also known as Pol eta.
Gene ID
11201
Gene Name (eCommerce)
DNA polymerase iota
Gene Name (Vector)
DNA polymerase iota
Gene Symbol
POLI
HGNC ID
HGNC:9182
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2148
ORF Size (bp)
2148 bp
Protein Name (eCommerce)
DNA polymerase iota
RefSeq ID
NM_007195
RefSeq Synonyms
NM_007195, BC032662,
Research Areas
DNA Damage/Repair,DNA Replication,Fanconi anemia
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Pol Iota is a DNA polymerase involved in DNA repair and translesion DNA synthesis. Pol Iota is a member of the Rad30 family of DNA polymerases which exhibit low fidelity when replicating undamaged DNA, and in this context may play a role in the hypermutation of immunoglobulin genes. Pol Iota is also known as RAD30B and is a paralog of RAD30A, also known as Pol eta.
UniGene ID
Hs.438533
UniProt ID (eCommerce)
Q9UNA4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.