human PAX8 Adenovirus

Name 
Ad-h-PAX8
Cat No 
ADV-218282
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GATA3.

ADV-218282
Ad-h-PAX8

Ready-to-use Adenovirus expressing Human PAX8 (paired box 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
paired box protein Pax-8;paired domain gene 8
Description (eCommerce)
PAX8 is a member of the paired box (PAX) family of transcription factors. PAX8 is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. [taken from NCBI Entrez Gene (Gene ID: 7849)].
Description (Vector)
PAX8 encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
7849
Gene Name (eCommerce)
paired box 8
Gene Name (Vector)
paired box 8
Gene Symbol
PAX8
HGNC ID
HGNC:8622
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1353
ORF Size (bp)
1353 bp
Protein Name (eCommerce)
Paired box protein Pax-8
RefSeq ID
NM_003466
RefSeq Synonyms
NM_013992, NM_013953, NM_013952, NM_003466, BC001060,
Research Areas
Apoptosis,Cancer,Neurobiology,Neurodevelopment,Signal Transduction,Transcription Factor / Regulator,Transcriptional Misregulation in Cancer,TSH Signaling
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
PAX8 is a member of the paired box (PAX) family of transcription factors. PAX8 is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. [taken from NCBI Entrez Gene (Gene ID: 7849)].
UniGene ID
Hs.469728
UniProt ID (eCommerce)
Q06710

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.