human OLR1 Adenovirus

Name 
Ad-h-OLR1
Cat No 
ADV-217413
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human OLR1.

ADV-217413
Ad-h-OLR1

Ready-to-use Adenovirus expressing Human OLR1 (oxidized low density lipoprotein receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CLEC8A; C-type lectin domain family 8 member A; hLOX-1; Lectin-like oxidized LDL receptor 1; Lectin-like oxLDL receptor 1; lectin-type oxidized LDL receptor 1; LOX1; LOX-1; LOXIN; ox LDL receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; Ox-LDL receptor 1; SCARE1; scavenger receptor class E, member 1; SLOX1
Description (eCommerce)
LOX-1 is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. LOX-1 binds, internalizes and degrades oxidized low-density lipoprotein and is regulated through the cyclic AMP signaling pathway. LOX-1 is also involved in the regulation of Fas-induced apoptosis and may play a role as a scavenger receptor. [taken from NCBI Entrez Gene (Gene ID: 4973)].
Description (Vector)
OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. OLR1 is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Gene ID
4973
Gene Name (eCommerce)
oxidized low density lipoprotein receptor 1
Gene Name (Vector)
oxidized low density lipoprotein receptor 1
Gene Symbol
OLR1
HGNC ID
HGNC:8133
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
822
Protein Name (eCommerce)
Oxidized low-density lipoprotein receptor 1
RefSeq ID
NM_002543
RefSeq Synonyms
NM_002543, NM_001172633, NM_001172632, BC022295,
Research Areas
Apoptosis,Cardiovascular,Immunology,Signal Transduction
Research Areas (Faceted)
cardiovascular,signal_transduction,cell_biology,immunology
Species
human
Target Sentence
LOX-1 is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. LOX-1 binds, internalizes and degrades oxidized low-density lipoprotein and is regulated through the cyclic AMP signaling pathway. LOX-1 is also involved in the regulation of Fas-induced apoptosis and may play a role as a scavenger receptor. [taken from NCBI Entrez Gene (Gene ID: 4973)].
UniGene ID
Hs.412484
UniProt ID (eCommerce)
P78380

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.