human NOX1 Adenovirus
This is an Adenovirus expressing Human NOX1.
ADV-216922
Ad-h-NOX1
Ready-to-use Adenovirus expressing Human NOX1 (NADPH oxidase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GP91-2; MOX1; NOH-1; NOH1
Description (Vector)
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
27035
Gene Name (Vector)
NADPH oxidase 1
Gene Symbol
NOX1
HGNC ID
HGNC:7889
ORF Size (aa)
1695
ORF Size (bp)
1695 bp
RefSeq ID
NM_007052
RefSeq Synonyms
NM_013955, NM_007052, NM_001271815, BC075015, BC075014,
Species
human
UniGene ID
Hs.592227
Related Citations
- Zinc regulates Nox1 expression through a NF-¿B and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells. Salazar G, etc, (2017), Free Radical Biology and Medicine
- Blackberry, raspberry and black raspberry polyphenol extracts attenuate angiotensin II-induced senescence in vascular smooth muscle cells. Feresin, R. etc, (2016), Food & Function
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.