human NFATC3 Adenovirus

Name 
Ad-h-NFATC3
Cat No 
ADV-216634
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human NFATC3.

ADV-216634
Ad-h-NFATC3

Ready-to-use Adenovirus expressing Human NFATC3 (nuclear factor of activated T-cells 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NFAT4; NF-AT4; NFATc3; NF-ATc3; NFATX; nuclear factor of activated T-cells c3 isoform IE-Xa; nuclear factor of activated T-cells, cytoplasmic 3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; T cell transcription factor NFAT4; T-cell transcription factor NFAT4
Description (eCommerce)
Nuclear factor of activated T cells, cytoplasmic 1(NFATc3) is a member of the NFAT family of transcription factors which includes NFAT1 (NFATp/NFATc2), NFAT2 (NFATc/NFATc1), NFAT3 (NFATc4), and NFAT4 (NFATc3/NFATx). Different members of the NFAT family are expressed in a distinct but overlapping set of cell types. NFATc3 plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of IL-2.
Description (Vector)
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
4775
Gene Name (eCommerce)
nuclear factor of activated T cells 3
Gene Name (Vector)
nuclear factor of activated T-cells 3
Gene Symbol
NFATC3
HGNC ID
HGNC:7777
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3228
ORF Size (bp)
3228 bp
Protein Name (eCommerce)
Nuclear factor of activated T-cells, cytoplasmic 3
RefSeq ID
NM_004555
RefSeq Synonyms
NM_173165, NM_173163, NM_004555, BC001050,
Research Areas
Axon Guidance,B-cell Receptor Signaling,Cancer,Cardiac Development,Cardiology,Cardiovascular,Fc Receptor Signaling,Host-Virus Interactions,Immunology,Innate Immunity,MAPK Signaling,Neurobiology,NFAT Signaling,Signal Transduction,T-cell Receptor Signaling,Transcription Factor/Regulator,Wnt Signaling
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,developmental_biology,immunology,infectious_disease,neurobiology,signal_transduction,transcription_translation
Species
human
Target Sentence
Nuclear factor of activated T cells, cytoplasmic 1(NFATc3) is a member of the NFAT family of transcription factors which includes NFAT1 (NFATp/NFATc2), NFAT2 (NFATc/NFATc1), NFAT3 (NFATc4), and NFAT4 (NFATc3/NFATx). Different members of the NFAT family are expressed in a distinct but overlapping set of cell types. NFATc3 plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of IL-2.
UniGene ID
Hs.632209
UniProt ID (eCommerce)
Q12968

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.