human NASP Adenovirus

Name 
Ad-h-NASP
Cat No 
ADV-216331
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human FAM64A.

ADV-216331
Ad-h-NASP

Ready-to-use Adenovirus expressing Human NASP (nuclear autoantigenic sperm protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
FLB7527; histone H1-binding protein; HMDRA1; NASP; NASP histone chaperone; nuclear autoantigenic sperm protein; nuclear autoantigenic sperm protein (histone-binding); PRO1999
Description (eCommerce)
NASP (Nuclear Autoantigenic Sperm Protein) is a component of a multichaperone nucleosome-remodeling complex that shuttles histones and coordinates their deposition in new nucleosomes. NASP functions as an H1 histone chaperone that transports H1 histones into the nucleus and exchanges H1 histones with DNA. NASP has been demonstrated to be required for DNA replication and cell cycle progression.
Description (Vector)
NASP encodes a H1 histone binding protein that is involved in transporting histones into the nucleus of dividing cells. Multiple isoforms are encoded by transcript variants of this gene. The somatic form is expressed in all mitotic cells, is localized to the nucleus, and is coupled to the cell cycle. The testicular form is expressed in embryonic tissues, tumor cells, and the testis. In male germ cells, this protein is localized to the cytoplasm of primary spermatocytes, the nucleus of spermatids, and the periacrosomal region of mature spermatozoa.
Gene ID
4678
Gene Name (eCommerce)
nuclear autoantigenic sperm protein
Gene Name (Vector)
nuclear autoantigenic sperm protein
Gene Symbol
NASP
HGNC ID
HGNC:7644
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2367
ORF Size (bp)
2367 bp
Protein Name (eCommerce)
Nuclear autoantigenic sperm protein
RefSeq ID
NM_002482
RefSeq Synonyms
NM_152298, NM_002482, NM_001195193, BC053608, BC011580, BC010105, BC003113,
Research Areas
Cell Cycle,DNA Replication,Histone Modification,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
NASP (Nuclear Autoantigenic Sperm Protein) is a component of a multichaperone nucleosome-remodeling complex that shuttles histones and coordinates their deposition in new nucleosomes. NASP functions as an H1 histone chaperone that transports H1 histones into the nucleus and exchanges H1 histones with DNA. NASP has been demonstrated to be required for DNA replication and cell cycle progression.
UniGene ID
Hs.319334
UniProt ID (eCommerce)
P49321

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.