human MUM1 Adenovirus

Name 
Ad-h-MUM1
Cat No 
ADV-216082
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MUM1.

ADV-216082
Ad-h-MUM1

Ready-to-use Adenovirus expressing Human MUM1 (melanoma associated antigen (mutated) 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EXPAND1; HSPC211; melanoma ubiquitous mutated protein; MUM-1; mutated melanoma-associated antigen 1; protein expandere; PWWP domain-containing protein MUM1
Description (eCommerce)
Mutated melanoma-associated antigen 1 (MUM1) is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. MUM1 is recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. MUM1 is required for efficient DNA repair and cell survival following DNA damage [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q2TAK8].
Gene ID
84939
Gene Name (eCommerce)
melanoma associated antigen (mutated) 1
Gene Name (Vector)
melanoma associated antigen (mutated) 1
Gene Symbol
MUM1
HGNC ID
HGNC:29641
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2199
ORF Size (bp)
2199 bp
Protein Name (eCommerce)
PWWP domain-containing protein MUM1
RefSeq ID
NM_032853
RefSeq Synonyms
NM_032853, BC144138, BC130443, BC110874, BC019585, BC008098,
Research Areas
Chromatin Remodeling,DNA Damage/Repair
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
Mutated melanoma-associated antigen 1 (MUM1) is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. MUM1 is recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. MUM1 is required for efficient DNA repair and cell survival following DNA damage [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q2TAK8].
UniGene ID
Hs.515016
UniProt ID (eCommerce)
Q2TAK8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.