human MTHFR Adenovirus

Name 
Ad-h-MTHFR
Cat No 
ADV-215996
Availability
4-5 weeks

This is an Adenovirus expressing Human FAM136A.

ADV-215996
Ad-h-MTHFR

Ready-to-use Adenovirus expressing Human MTHFR (methylenetetrahydrofolate reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
5,10-methylenetetrahydrofolate reductase (NADPH); methylenetetrahydrofolate reductase; methylenetetrahydrofolate reductase (NAD(P)H)
Description (eCommerce)
Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
Description (Vector)
MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
Gene ID
4524
Gene Name (eCommerce)
methylenetetrahydrofolate reductase
Gene Name (Vector)
methylenetetrahydrofolate reductase
Gene Symbol
MTHFR
HGNC ID
HGNC:7436
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1971
ORF Size (bp)
1971 bp
Protein Name (eCommerce)
Methylenetetrahydrofolate reductase
RefSeq ID
NM_005957
RefSeq Synonyms
NM_005957, NM_001330358, BC053509,
Research Areas
Cancer,Cardiovascular,Metabolism/Metabolic Process,Neurobiology,Neurodegeneration,Parkinson's Disease
Research Areas (Faceted)
cancer,cardiovascular,cell_biology,metabolism,neurobiology
Species
human
Target Sentence
Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine.
UniGene ID
Hs.214142
UniProt ID (eCommerce)
P42898

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.