human MMP8 Adenovirus
This is an Adenovirus expressing Human MMP8.
ADV-215604
Ad-h-MMP8
Ready-to-use Adenovirus expressing Human MMP8 (matrix metallopeptidase 8). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CLG1; HNC; MMP-8; PMNL-CL
Description (Vector)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Gene ID
4317
Gene Name (Vector)
matrix metallopeptidase 8
Gene Symbol
MMP8
HGNC ID
HGNC:7175
ORF Size (aa)
1404
ORF Size (bp)
1404 bp
RefSeq ID
NM_002424
RefSeq Synonyms
NM_002424, NM_001304442, NM_001304441, BC074989, BC074988,
Species
human
UniGene ID
Hs.161839
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.