Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

MERTK

Gene Name

MER proto-oncogene, tyrosine kinase

Gene ID

10461

Gene Synonyms

c-Eyk; c-mer; MER; RP38; Tyro12

ORF Size

2472 bp

RefSeq#

BC114917

Gene Description

MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

UniGene ID

Hs.306178

HGNC ID

HGNC:7027