human MASTL Adenovirus

Name
Ad-h-MASTL

Cat No
ADV-215061

Availability
4-5 weeks

This is an Adenovirus expressing Human MASTL.

ADV-215061

Ad-h-MASTL

Ready-to-use Adenovirus expressing Human MASTL (microtubule associated serine/threonine kinase like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

GREATWALL; greatwall kinase homolog; greatwall protein kinase; GW; GWL; hGWL; MAST-L; Microtubule-associated serine/threonine-protein kinase-like; serine/threonine-protein kinase greatwall; THC2

Description (eCommerce)

MASTL (microtubule-associated serine/threonine-protein kinase-like) is an uncharacterized putative serine/threonine kinase which may be involved in megakaryocyte development. Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) a disease characterized by decreased circulating platelets and increased potential for bleeding.

Description (Vector)

MASTL encodes a microtubule-associated serine/threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia-2. Alternatively spliced transcript variants have been described for this locus.

Gene ID

84930

Gene Name (eCommerce)

microtubule associated serine/threonine kinase like

Gene Name (Vector)

microtubule associated serine/threonine kinase like

Gene Symbol

MASTL

HGNC ID

HGNC:19042

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

2640

ORF Size (bp)

2640 bp

Protein Name (eCommerce)

Serine/threonine-protein kinase greatwall

RefSeq ID

NM_032844

RefSeq Synonyms

NM_032844, NM_001320757, NM_001320756, NM_001172304, NM_001172303, BC009107,

Research Areas

Cell Cycle,Cell Division,Cytoskeleton,DNA Damage/Repair,Kinase/Phosphatase,Signal Transduction

Research Areas (Faceted)

signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,cell_biology

Species

human

Target Sentence

MASTL (microtubule-associated serine/threonine-protein kinase-like) is an uncharacterized putative serine/threonine kinase which may be involved in megakaryocyte development. Defects in MASTL are the cause of thrombocytopenia type 2 (THC2) a disease characterized by decreased circulating platelets and increased potential for bleeding.

UniGene ID

Hs.276905

UniProt ID (eCommerce)

Q96GX5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.