human MAFA Adenovirus
This is an Adenovirus expressing Human MAFA.
ADV-214792
Ad-h-MAFA
Ready-to-use Adenovirus expressing Human MAFA (MAF bZIP transcription factor A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hMafA; INSDM; pancreatic beta-cell-specific transcriptional activator; RIPE3b1; RIPE3b1 factor; transcription factor MafA; transcription factor RIPE3b1; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A; V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
Description (eCommerce)
MafA is a member of the Maf basic leucine-zipper containing transcription factor family. MafA is an islet-enriched protein that plays a role in beta cell-specific and glucose-responsive insulin gene transcription. MafA is expressed exclusively in cell populations that will become islet beta cells.
Description (Vector)
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 (PubMed 12011435)).(supplied by OMIM, Mar 2008)
Gene ID
389692
Gene Name (eCommerce)
MAF bZIP transcription factor A
Gene Name (Vector)
MAF bZIP transcription factor A
Gene Symbol
MAFA
HGNC ID
HGNC:23145
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1059
ORF Size (bp)
1059 bp
Protein Name (eCommerce)
Transcription factor MafA
RefSeq ID
NM_201589
RefSeq Synonyms
NM_201589, BC156443,
Research Areas
Gene Expression
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
MafA is a member of the Maf basic leucine-zipper containing transcription factor family. MafA is an islet-enriched protein that plays a role in beta cell-specific and glucose-responsive insulin gene transcription. MafA is expressed exclusively in cell populations that will become islet beta cells.
UniGene ID
Hs.670866
UniProt ID (eCommerce)
Q8NHW3
Related Citations
- Spheroid Fabrication Using Concave Microwells Enhances the Differentiation Efficacy and Function of Insulin-Producing Cells via Cytoskeletal Changes. YN Lee, etc, (2020), Cells
- Enhanced insulin production and reprogramming efficiency of mesenchymal stem cells derived from porcine pancreas using suitable induction medium. S Lee, S, (2018), Xenotransplantation
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.