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human MAD1L1 Adenovirus

Name 
Ad-h-MAD1L1
Cat No 
ADV-214774
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MAD1L1.

ADV-214774
Ad-h-MAD1L1

Ready-to-use Adenovirus expressing Human MAD1L1 (MAD1 mitotic arrest deficient like 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
hMAD1; HsMAD1; MAD1; MAD1 mitotic arrest deficient like 1; MAD1-like protein 1; mitotic arrest deficient 1-like protein 1; mitotic checkpoint MAD1 protein homolog; mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; PIG9; tax-binding protein 181; TP53I9; tumor protein p53 inducible protein 9; TXBP181
Description (eCommerce)
MAD1 (Mitotic Arrest Deficiency 1) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD1 functions as a homodimer that interacts with and regulates MAD2. MAD1 may play a role in tumor suppression.
Description (Vector)
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
8379
Gene Name (eCommerce)
mitotic arrest deficient 1 like 1
Gene Name (Vector)
MAD1 mitotic arrest deficient like 1
Gene Symbol
MAD1L1
HGNC ID
HGNC:6762
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2157
ORF Size (bp)
2157 bp
Protein Name (eCommerce)
Mitotic spindle assembly checkpoint protein MAD1
RefSeq ID
NM_003550
RefSeq Synonyms
NM_003550, NM_001304525, NM_001304524, NM_001304523, NM_001013837, NM_001013836, BC009964,
Research Areas
Cancer,Cell Cycle,Cell Division,Cytoskeleton,Host-Virus Interactions,Mitochondrion,Tumor Suppressors/Oncoproteins,Viral Carcinogenesis
Research Areas (Faceted)
cancer,cell_biology,cell_cycle,genetics,infectious_disease
Species
human
Target Sentence
MAD1 (Mitotic Arrest Deficiency 1) is a component of the mitotic spindle-assembly checkpoint that ensures that all chromosomes are aligned at the metaphase plate before the onset of anaphase. MAD1 functions as a homodimer that interacts with and regulates MAD2. MAD1 may play a role in tumor suppression.
UniGene ID
Hs.654838
UniProt ID (eCommerce)
Q9Y6D9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.