human LRP6 Adenovirus
This is an Adenovirus expressing Human EDIL3.
ADV-214508
Ad-h-LRP6
Ready-to-use Adenovirus expressing Human LRP6 (LDL receptor related protein 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ADCAD2; STHAG7
Description (Vector)
LRP6 encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
Gene ID
4040
Gene Name (Vector)
LDL receptor related protein 6
Gene Symbol
LRP6
HGNC ID
HGNC:6698
ORF Size (aa)
4842
ORF Size (bp)
4842 bp
RefSeq ID
NM_002336
RefSeq Synonyms
NM_002336, BC143725, BC126405, BC117136,
Species
human
UniGene ID
Hs.658913
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.