human KCNA1 Adenovirus
This is an Adenovirus expressing Human KCNA1.
ADV-212649
Ad-h-KCNA1
Ready-to-use Adenovirus expressing Human KCNA1 (potassium voltage-gated channel subfamily A member 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1
Description (Vector)
KCNA1 encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Gene ID
3736
Gene Name (Vector)
potassium voltage-gated channel subfamily A member 1
Gene Symbol
KCNA1
HGNC ID
HGNC:6218
ORF Size (aa)
1488
ORF Size (bp)
1488 bp
RefSeq ID
NM_000217
RefSeq Synonyms
NM_000217, BC112180, BC101733,
Species
human
UniGene ID
Hs.416139
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.