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human IL21 Adenovirus

Name 
Ad-h-IL21
Cat No 
ADV-212139
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IL21.

ADV-212139
Ad-h-IL21

Ready-to-use Adenovirus expressing Human IL21 (interleukin 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CVID11; IL-21; Za11
Description (Vector)
IL21 encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
59067
Gene Name (Vector)
interleukin 21
Gene Symbol
IL21
HGNC ID
HGNC:6005
ORF Size (aa)
489
RefSeq ID
NM_021803
RefSeq Synonyms
NM_021803, NM_001207006, BC069124, BC066262, BC066261, BC066260, BC066259, BC066258,
Species
human
UniGene ID
Hs.567559

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.