human PDE1B Adenovirus

Name
Ad-h-PDE1B

Cat No
ADV-218462

Availability
4-5 weeks

This is an Adenovirus expressing Human PDE1B.

ADV-218462

Ad-h-PDE1B

Ready-to-use Adenovirus expressing Human PDE1B (phosphodiesterase 1B). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

HEL-S-79p; PDE1B1; PDES1B

Description (Vector)

PDE1B belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

5153

Gene Name (Vector)

phosphodiesterase 1B

Gene Symbol

PDE1B

HGNC ID

HGNC:8775

ORF Size (aa)

1611

ORF Size (bp)

1611 bp

RefSeq ID

NM_000924

RefSeq Synonyms

NM_001315535, NM_001315534, NM_001288769, NM_001288768, NM_001165975, NM_000924, BC032226,

Species

human

UniGene ID

Hs.530871

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.