human IL19 Adenovirus

Name 
Ad-h-IL19
Cat No 
ADV-212088
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human IL19.

ADV-212088
Ad-h-IL19

Ready-to-use Adenovirus expressing Human IL19 (interleukin 19). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
IL-10C; MDA1; NG.1; ZMDA1
Description (Vector)
IL19 is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
Gene ID
29949
Gene Name (Vector)
interleukin 19
Gene Symbol
IL19
HGNC ID
HGNC:5990
ORF Size (aa)
645
RefSeq ID
NM_013371
RefSeq Synonyms
NM_153758, NM_013371, BC172584, BC153127, BC148534,
Species
human
UniGene ID
Hs.661017

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.