human HSD3B2 Adenovirus

Name
Ad-h-HSD3B2

Cat No
ADV-211584

Availability
4-5 weeks

This is an Adenovirus expressing Human HSD3B2.

ADV-211584

Ad-h-HSD3B2

Ready-to-use Adenovirus expressing Human HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

HSD3B; HSDB; SDR11E2

Description (Vector)

HSD3B2 is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

Gene ID

3284

Gene Name (Vector)

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

Gene Symbol

HSD3B2

HGNC ID

HGNC:5218

ORF Size (aa)

1119

ORF Size (bp)

1119 bp

RefSeq ID

NM_000198

RefSeq Synonyms

NM_001166120, NM_000198, BC131488, BC038419,

Species

human

UniGene ID

Hs.654399

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.