human HMGB2 Adenovirus

Name 
Ad-h-HMGB2
Cat No 
ADV-211276
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human HMGB2.

ADV-211276
Ad-h-HMGB2

Ready-to-use Adenovirus expressing Human HMGB2 (high mobility group box 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HMG2
Description (Vector)
HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.
Gene ID
3148
Gene Name (Vector)
high mobility group box 2
Gene Symbol
HMGB2
HGNC ID
HGNC:5000
ORF Size (aa)
630
RefSeq ID
NM_002129
RefSeq Synonyms
NM_002129, NM_001130689, NM_001130688, BC100019, BC001063,
Species
human
UniGene ID
Hs.434953

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.