human HIP1R Adenovirus

Name 
Ad-h-HIP1R
Cat No 
ADV-211039
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human HIP1R.

ADV-211039
Ad-h-HIP1R

Ready-to-use Adenovirus expressing Human HIP1R (huntingtin interacting protein 1 related). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HIP12; HIP-12; HIP1-related protein; HIP3; huntingtin interacting protein 12; Huntingtin-interacting protein 12; huntingtin-interacting protein 1-related protein; ILWEQ
Description (eCommerce)
HIP1R is a component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. It binds 3-phosphoinositides (via ENTH domain). HIP1R may act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75146].
Gene ID
9026
Gene Name (eCommerce)
huntingtin interacting protein 1 related
Gene Name (Vector)
huntingtin interacting protein 1 related
Gene Symbol
HIP1R
HGNC ID
HGNC:18415
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1848
ORF Size (bp)
1848 bp
Protein Name (eCommerce)
Huntingtin-interacting protein 1-related protein
RefSeq ID
NM_003959
RefSeq Synonyms
NM_003959, NM_001303099, NM_001303097, BC067085,
Research Areas
Cytoskeleton,Golgi Apparatus
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
HIP1R is a component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. It binds 3-phosphoinositides (via ENTH domain). HIP1R may act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O75146].
UniGene ID
Hs.714965
UniProt ID (eCommerce)
O75146

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.