human HDAC7 Adenovirus
This is an Adenovirus expressing Human HDAC7.
ADV-210893
Ad-h-HDAC7
Ready-to-use Adenovirus expressing Human HDAC7 (histone deacetylase 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HD7; HD7A; HDAC7A; histone deacetylase 7; histone deacetylase 7A
Description (eCommerce)
Histone deacetylase 7 (HDAC7) is a class II histone deacetylase that catalyzes the removal of acetyl groups from core histone octamer subunits. HDAC7 appears to have an influence on cellular processes by acting as a transcriptional repressor. HDAC7 is highly expressed in double positive thymocytes and may play an important role in T-cell development. Recently, HDAC7 has also been reported to influence endothelial cell migration and modulate angiogenesis.
Description (Vector)
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
51564
Gene Name (eCommerce)
histone deacetylase 7
Gene Name (Vector)
histone deacetylase 7
Gene Symbol
HDAC7
HGNC ID
HGNC:14067
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2865
ORF Size (bp)
2865 bp
Protein Name (eCommerce)
Histone deacetylase 7
RefSeq ID
NM_015401
RefSeq Synonyms
NM_015401, NM_001308090, NM_001098416, BC064840, BC006453,
Research Areas
Cancer,Cardiac Hypertrophy,Cardiology,Cardiovascular,Cell Cycle,Chromatin Remodeling,Histone Modification,Host-Virus Interactions,Immunology,Neurobiology,Neurodevelopment,Notch Signaling,Signal Transduction,T-cell Receptor Signaling,TGF-beta Signaling,Transcription Factor/Regulator,Viral Carcinogenesis
Research Areas (Faceted)
cancer,signal_transduction,cardiovascular,cell_biology,cell_cycle,transcription_translation,genetics,infectious_disease,immunology,neurobiology,developmental_biology,developmental_biology,signal_transduction,immunology,genetics,transcription_translation,cancer,infectious_disease
Species
human
Target Sentence
Histone deacetylase 7 (HDAC7) is a class II histone deacetylase that catalyzes the removal of acetyl groups from core histone octamer subunits. HDAC7 appears to have an influence on cellular processes by acting as a transcriptional repressor. HDAC7 is highly expressed in double positive thymocytes and may play an important role in T-cell development. Recently, HDAC7 has also been reported to influence endothelial cell migration and modulate angiogenesis.
UniGene ID
Hs.200063
UniProt ID (eCommerce)
Q8WUI4
Recently Viewed Products
Ad-h-TMEM188
Cat No: ADV-225825
Ad-h-BPIL2-shRNA
Cat No: shADV-202242
AAV-h-RNF216-shRNA
Cat No: shAAV-221411
AAV-h-HPS4-shRNA
Cat No: shAAV-211504
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.