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human GTSE1 Adenovirus

Name 
Ad-h-GTSE1
Cat No 
ADV-210668
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GTSE1.

ADV-210668
Ad-h-GTSE1

Ready-to-use Adenovirus expressing Human GTSE1 (G2 and S-phase expressed 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
B99; G2 and S phase-expressed protein 1; G-2 and S-phase expressed 1; GTSE-1; protein B99 homolog
Description (eCommerce)
GTSE1 (G-2 and S-phase expressed 1) is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, GTSE1 accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis [taken from NCBI Entrez Gene (GeneID: 51512)].
Description (Vector)
GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.
Gene ID
51512
Gene Name (eCommerce)
G2 and S-phase expressed 1
Gene Name (Vector)
G2 and S-phase expressed 1
Gene Symbol
GTSE1
HGNC ID
HGNC:13698
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2163
ORF Size (bp)
2163 bp
Protein Name (eCommerce)
G2 and S phase-expressed protein 1
RefSeq ID
NM_016426
RefSeq Synonyms
NM_016426, BC075828, BC006325,
Research Areas
Cell Cycle,Cytoskeleton,DNA Damage/Repair,p53 Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,signal_transduction
Species
human
Target Sentence
GTSE1 (G-2 and S-phase expressed 1) is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, GTSE1 accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis [taken from NCBI Entrez Gene (GeneID: 51512)].
UniGene ID
Hs.386189
UniProt ID (eCommerce)
Q9NYZ3

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.