human GTPBP4 Adenovirus

Name 
Ad-h-GTPBP4
Cat No 
ADV-210665
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GTPBP4.

ADV-210665
Ad-h-GTPBP4

Ready-to-use Adenovirus expressing Human GTPBP4 (GTP binding protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
chronic renal failure gene protein; CRFG; G protein-binding protein CRFG; GTP-binding protein NGB; NGB; NOG1; nucleolar GTP-binding protein 1
Description (eCommerce)
GTP-binding protein 4 (GTPBP4) belongs to the NOG (nucleolar GTP) subfamily of the GTP1/OBG family. By similarity, GTPBP4 may be involved in biogenesis of the 60S ribosomal subunit.
Description (Vector)
GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
Gene ID
23560
Gene Name (eCommerce)
GTP binding protein 4
Gene Name (Vector)
GTP binding protein 4
Gene Symbol
GTPBP4
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1905
ORF Size (bp)
1905 bp
Protein Name (eCommerce)
Nucleolar GTP-binding protein 1
RefSeq ID
NM_012341
RefSeq Synonyms
NM_012341, BC038975,
Research Areas
DNA Replication,Golgi Apparatus,Signal Transduction
Research Areas (Faceted)
signal_transduction,genetics,transcription_translation,cell_biology
Species
human
Target Sentence
GTP-binding protein 4 (GTPBP4) belongs to the NOG (nucleolar GTP) subfamily of the GTP1/OBG family. By similarity, GTPBP4 may be involved in biogenesis of the 60S ribosomal subunit.
UniGene ID
Hs.215766
UniProt ID (eCommerce)
Q9BZE4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.