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human GREM2 Adenovirus

Name 
Ad-h-GREM2
Cat No 
ADV-210495
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GREM2.

ADV-210495
Ad-h-GREM2

Ready-to-use Adenovirus expressing Human GREM2 (gremlin 2, DAN family BMP antagonist). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CKTSF1B2; DAND3; PRDC
Description (Vector)
GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.
Gene ID
64388
Gene Name (Vector)
gremlin 2, DAN family BMP antagonist
Gene Symbol
GREM2
HGNC ID
HGNC:17655
ORF Size (aa)
507
RefSeq ID
NM_022469
RefSeq Synonyms
NM_022469, BC046632,
Species
human
UniGene ID
Hs.98206

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.