human GPBAR1 Adenovirus
This is an Adenovirus expressing Human GPBAR1.
ADV-210213
Ad-h-GPBAR1
Ready-to-use Adenovirus expressing Human GPBAR1 (G protein-coupled bile acid receptor 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BG37; GPCR19; GPR131; M-BAR; TGR5
Description (Vector)
GPBAR1 encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene ID
151306
Gene Name (Vector)
G protein-coupled bile acid receptor 1
Gene Symbol
GPBAR1
HGNC ID
HGNC:19680
ORF Size (aa)
993
ORF Size (bp)
993 bp
RefSeq ID
NM_170699
RefSeq Synonyms
NM_170699, NM_001321950, NM_001077194, NM_001077191, BC033625,
Species
human
UniGene ID
Hs.160954
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.