human GGCT Adenovirus

Name 
Ad-h-GGCT
Cat No 
ADV-209841
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human GGCT.

ADV-209841
Ad-h-GGCT

Ready-to-use Adenovirus expressing Human GGCT (gamma-glutamylcyclotransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
C7orf24; CRF21; cytochrome c-releasing factor 21; gamma -glutamyl cyclotransferase; gamma-glutamylcyclotransferase; GCTG; GGC
Description (eCommerce)
Gamma-glutamylcyclotransferase (GGCT) catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. GGCT may also play a role in cell proliferation, and the expression of GGCT is a potential marker for cancer [taken from NCBI Entrez Gene (Gene ID: 79017)].
Description (Vector)
GGCT catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
79017
Gene Name (eCommerce)
gamma-glutamylcyclotransferase
Gene Name (Vector)
gamma-glutamylcyclotransferase
Gene Symbol
GGCT
HGNC ID
HGNC:21705
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
567
Protein Name (eCommerce)
Gamma-glutamylcyclotransferase
RefSeq ID
NM_024051
RefSeq Synonyms
NM_024051, NM_001199817, NM_001199816, NM_001199815, BC019243, BC013937, BC005356, BC000625,
Research Areas
Acyltransferase,Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Gamma-glutamylcyclotransferase (GGCT) catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. GGCT may also play a role in cell proliferation, and the expression of GGCT is a potential marker for cancer [taken from NCBI Entrez Gene (Gene ID: 79017)].
UniGene ID
Hs.530024
UniProt ID (eCommerce)
O75223

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.