human GAD1 Adenovirus
This is an Adenovirus expressing Human GAD1.
ADV-209536
Ad-h-GAD1
Ready-to-use Adenovirus expressing Human GAD1 (glutamate decarboxylase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CPSQ1; GAD; SCP
Description (Vector)
GAD1 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. GAD1 may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Gene ID
2571
Gene Name (Vector)
glutamate decarboxylase 1
Gene Symbol
GAD1
HGNC ID
HGNC:4092
ORF Size (aa)
1278
ORF Size (bp)
1278 bp
RefSeq ID
NM_000817
RefSeq Synonyms
NM_013445, NM_000817, BC037780, BC036552, BC026349, BC002815,
Species
human
UniGene ID
Hs.420036
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.