human GABRD Adenovirus

Name 
Ad-h-GABRD
Cat No 
ADV-209521
Availability
4-5 weeks

This is an Adenovirus expressing Human GABRD.

ADV-209521
Ad-h-GABRD

Ready-to-use Adenovirus expressing Human GABRD (gamma-aminobutyric acid type A receptor delta subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
EIG10; EJM7; GEFSP5
Description (Vector)
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.
Gene ID
2563
Gene Name (Vector)
gamma-aminobutyric acid type A receptor delta subunit
Gene Symbol
GABRD
HGNC ID
HGNC:4084
ORF Size (aa)
1359
ORF Size (bp)
1359 bp
RefSeq ID
NM_000815
RefSeq Synonyms
NM_000815, BC033801,
Species
human
UniGene ID
Hs.113882

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.